CMD To Reboot To BIOS Settings
Instead of guessing which F key will magically boot to the BIOS settings.
Open an admin command prompt (be sure you are in system32 directory).
shutdown /r /fw
shutdown /r /fw /f /t 0
/r reboot
/fw boot to firmware interface
/f force shutdown
/t 0 no wait time
CMD To Reboot To Safe Mode
bcdedit /set {current} safeboot minimal
bcdedit /set {current} safeboot network
(Win10+ is hopeless at WiFi in safe mode so have a cable handy)
When leaving Safe Mode
bcdedit /deletevalue {current} safeboot
Bonus:
Safe Mode Launcher by Sordum is available in Symenu if interested.